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* [[Pseudoephedrine]] is a stimulant that used to be the most common ingredient in sinus drugs. Because of its role in the production of recreational drugs, it has been made more difficult to buy. Has some side effects and not meant for long term use. | * [[Pseudoephedrine]] is a stimulant that used to be the most common ingredient in sinus drugs. Because of its role in the production of recreational drugs, it has been made more difficult to buy. Has some side effects and not meant for long term use. | ||
* [[Phenylephrine]] has largely replaced pseudoephedrine in oral sinus medications. A nasal spray is also available. There is controversial evidence as to whether this has any effect or not, with some studies showing no more effect than a placebo, while the US Food and Drug Administration argues that it should be sold. | * [[Phenylephrine]] has largely replaced pseudoephedrine in oral sinus medications. A nasal spray is also available. There is controversial evidence as to whether this has any effect or not, with some studies showing no more effect than a placebo, while the US Food and Drug Administration argues that it should be sold. | ||
− | * [[Immunomodulators]] alter how the body responds to pathogens. This can prevent excessive production of symptoms by the body itself. | + | * [[Immunomodulators]] alter how the body responds to pathogens. This can prevent excessive production of symptoms by the body itself. |
* [[Antifungal]] agents have recently been tested, on the basis of cases of sinusitis having to do with fungal infections. [https://linkinghub.elsevier.com/retrieve/pii/S009545430700084X] | * [[Antifungal]] agents have recently been tested, on the basis of cases of sinusitis having to do with fungal infections. [https://linkinghub.elsevier.com/retrieve/pii/S009545430700084X] | ||
* Antibiotics are often prescribed. However, they have no effect on viral pathogens, they can have side effects include worsening the sinus symptoms, and overuse can breed resistant strains of bacteria. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251963/] | * Antibiotics are often prescribed. However, they have no effect on viral pathogens, they can have side effects include worsening the sinus symptoms, and overuse can breed resistant strains of bacteria. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251963/] |